東京科学大学
生命理工学院 門之園研究室

Achievements

論文(抜粋):

N. Lin, K. Miyamoto, T. Ogawara, S. Sakurai, S. Kizaka-Kondoh, T. Kadonosono*

“Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing”

Commun Biol, 7, 652 (2024)   >>PDF

 

T. Kadonosono, K. Miyamoto, S. Sakai, Y. Matsuo, S. Kitajima, Q. Wang, M. Endo, M. Niibori, T. Kuchimaru, T. Soga, K. Hirota, S. Kizaka-Kondoh*

“AGE/RAGE axis regulates reversible transition to quiescent states of ALK-rearranged NSCLC and pancreatic cancer cells in monolayer cultures”

Sci Rep, 12 (1), 9886 (2022)   >>PDF

 

K. See, T. Kadonosono*, K. Miyamoto, T. Tsubaki, Y. Ota, M. Katsumi, S. Ryo, K. Aida, M. Minegishi, T. Isozaki, T. Kuchimaru, S. Kizaka-Kondoh

“Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display”

Sci Rep, 11 (1), 22098 (2021)   >>PDF

 

K. See, T. Kadonosono*, Y. Ota, K. Miyamoto, W. Yimchuen, S. Kizaka-Kondoh

“Reconstitution of an anti-HER2 antibody paratope by grafting dual CDR-derived peptides onto a small protein scaffold”

Biotechnol J, 15(12), 2000078 (2020)   >>Journal site

 

W. Yimchuen, T. Kadonosono*, Y. Ota, S. Sato, M. Kitazawa, T. Shiozawa, T. Kuchimaru, M. Taki, Y. Ito, H. Nakamura, S. Kizaka-Kondoh

“Strategic design to create HER2-targeting proteins with target-binding peptides immobilized on a fibronectin type III domain scaffold”

RSC Adv, 10, 15154-15162 (2020)   >>PDF

 

T. Kadonosono, W. Yimchuen, Y. Ota, K. See, T. Furuta, T. Shiozawa, M. Kitazawa, A. Patil, T. Kuchimaru, S. Kizaka-Kondoh*

“Design strategy to create antibody mimetics harbouring immobilised complementarity determining region peptides for practical use”

Sci Rep, 10(1), 891 (2020)   >>PDF

 

著書(抜粋):

門之園 哲哉

中分子ペプチド医薬で新たな標的を狙う!!, 実験医学 (羊土社), 41(1), 2-55 (2023) (企画)

 

門之園 哲哉

シン・中分子ペプチド創薬への技術革新と進化, 実験医学「中分子ペプチド医薬で新たな標的を狙う!!」(羊土社), 41(1), 2-7 (2023)

 

門之園 哲哉, 近藤 科江

CDRペプチドの構造ゆらぎ制御による抗体代替小型タンパク質デザイン

ペプチド創薬の最前線 (シーエムシー出版), 第18章, 165-172 (2019)

 

論文(全件)、著書(全件)、招待講演、学会発表はこちら→T2R2Researchmap